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Lipex (Atorvastatin) is indicated in primary hypercholesterolaemia, heterozygous familial hypercholesterolaemia, homozygous familial hypercholesterolaemia or combined (mixed) hyperlipidaemia in patients who have not responded adequately to diet and other appropriate measures.

Reversible myositis is a rare but significant side-effects of Lipex (Atorvastatin) are myalgia, myopathy. Lipex (Atorvastatin) also causes headache, altered liver-function tests and gastrointestinal effects including abdominal pain, flatulence, diarrhoea, nausea and vomiting. Rash and hypersensitivity reactions have been reported rarely. Also insomnia, angioedema, anorexia, asthenia, paraesthesia, peripheral neuropathy, alopecia, pruritus, impotence, chest pain, hypoglycaemia, hyperglycaemia reported; thrombocytopenia reported rarely.

Hypercholesterolaemia and Mixed Dyslipidemia: The recommended starting dose of Lipex (Atorvastatin) is 10 or 20 mg once daily. Patients who require a large reduction in LDL-C (more than 45%) may be started at 40 mg once daily. The dosage range of Lipex (Atorvastatin) is 10 to 80 mg once daily. Homozygous Familial hypercholesterolaemia: The dosage of Lipex (Atorvastatin) in patients with homozygous FH is 10 to 80 mg daily. Heterozygous Familial hypercholesterolaemia in Pediatric Patients (10-17 years of age): The recommended starting dose of Lipex (Atorvastatin) is 10 mg/day; the maximum recommended dose is 20 mg/day (doses greater than 20 mg have not been studied in this patient population).